We protect your intellectual property

Biophotonics Consulting & Design & Development

Biophotonics is the established general term for all techniques that deal with the interaction between biological items and photons. In other words, Biophotonics deals with the interaction of organic matter and photons (light). This refers to emission, detection, absorption, reflection, modification, and creation of radiation from biomolecules, cells, tissues, organisms and biomaterials. Areas of application for biophotonics are life sciences, medicine, agriculture, and environmental science. Biophotonics can be used to study biological materials or materials with properties similar to biological materials on a microscopic and macroscopic scale. On the microscopic scale, applications include microscopy and optical coherence tomography. In microscopy, biophotonics deals with the development and refinement of the confocal microscope, the fluorescence microscope, and the total internal reflection fluorescence microscope. Specimens imaged with microscopic techniques can also be manipulated by biophotonic optical tweezers and laser micro-scalpels. On the macroscopic scale, the light is diffuse and applications commonly deal with Diffuse Optical Imaging (DOI) and Diffuse Optical Tomography (DOT). DOT is a method used to reconstruct an internal anomaly inside a scattering material. DOT is a non-invasive method only requiring the data collected at the boundaries. The procedure generally involves scanning a sample with a light source while collecting light that exits the boundaries. The collected light is then matched with a model, for example, the diffusion model, giving an optimization problem.

​

The most popular light sources used in biophotonics are lasers. However also LED´s, SLED´s or lamps play an important role. Typical wavelengths used in biophotonics are between 200 nm (UV) and 3000 nm (near IR). Lasers are important in Biophotonics. Their unique intrinsic properties like precise wavelength selection, widest wavelength coverage, high focusing capability, best spectral resolution, strong power densities and broad spectrum of excitation periods make them the most universal light tool for a wide spectrum of applications in biophotonics.

We work on projects relating to light, color, optics, lasers and biophotonics, including laser safety issues, hazard analysis and applications. Our engineers experience covers optical manipulation of biological systems on the cellular level and above. We are ready to handle consulting, design and development jobs with diverse requirements. We can undertake consulting work, design and contract R&D in our fields of expertise which include:
 

• Computer modelling, data analysis, simulations and image processing

• Laser applications in biophotonics

• Laser development (DPSS, Diode Laser, DPSL, etc.), specialty in medical and biotech applications. Analysis, verification and calculation of applicable laser safety class

• Biophysics & Biomems Consulting & Design & Development

• Optics and Photonics for biophotonics applications

• Optical thin-films (deposition and analysis) for biophotonic applications

• Optoelectronic device design, development and prototyping for biophotonic applications

• Working with Components for Photodynamic Therapy (PDT)

• Endoscopy

• Medical fiber optic assembly, test using fibers, adapters, couplers, , probes, fiberscopes…etc..

• Electrical & optical characterization of biophotonic devices and systems

• Development of autoclavable medical and biophotonics components

• Spectroscopy and optical diagnostics. Conduct laser-based spectroscopic studies with spectrally and temporally resolved imaging capabilities, and fluorescence and absorption spectrometry

• Polymer and chemical synthesis using lasers and light

• Study samples using optical microscopy, including confocal, far field and fluorescence imaging

• Nanotechnology consulting & development for biomedical applications

• Detection of single molecule fluorescence

• R&D and if needed we offer manufacturing under ISO 13485 quality systems and FDA compliant. Measurement and certification of devices under ISO standards 60825-1, 60601-1, 60601-1-2, 60601-2-22

• Training services in biophotonics and instrumentation

• Expert witness and litigation services.

We have access to a well-equipped lab with lasers, spectroscopy systems and associated devices in dedicated experimental laboratories. The laser systems enable us to access wavelengths between 157 nm – 2500 nm. Besides high-power CW systems, we have pulsed systems with pulse durations down to 130 femtoseconds for ultrafast spectroscopy. A range of detectors, such as cooled photon counting detectors and an intensified CCD camera, enable sensitive detection with imaging, spectrally resolved and time resolved capabilities. The lab also has dedicated laser tweezers systems, and a confocal microscope system with fluorescence imaging capabilities. Clean rooms and a polymer and general synthesis laboratory for sample preparation are also part of the facility.

If you are mostly interested in our general manufacturing capabilities instead of engineering capabilities, we recommend you to visit our custom manufacturing site http://www.agstech.net

​

Our FDA and CE approved medical products can be found on our medical products, consumables and equipment site http://www.agsmedical.com